QuantumCT Builds a Quantum Ecosystem for Drug Development

Connecticut’s QuantumCT — a public-private partnership accelerating the adoption of quantum technologies — is developing new quantum models, forging partnerships and strengthening the quantum workforce to improve drug development. 

“Currently available classical computer models are inadequate … QuantumCT researchers are working with companies to develop new quantum models and algorithms to make drug development faster, cheaper and safer,” the program’s Co-Principal Investigator and University of Connecticut (UConn) Vice President for Research Innovation and Entrepreneurship Pamir Alpay told GovCIO Media & Research. 

QuantumCT is a finalist in the National Science Foundation’s Regional Innovation Engines Program, a federal initiative that funds regions working to turn emerging technologies into practical tools and jobs. The program emphasizes “use-inspired” research that brings together universities, companies and local governments to develop deployable technology solutions.

Building Community Partnerships

Connecticut is home to major industry players in advanced manufacturing, national security and drug development, including Nobel Prize in Physics recipient Michel Devoret, one of the world’s foremost experts in quantum science and technology. 

“All the ingredients to drive the development of quantum technologies and their real-world applications are here,” said Alpay. “The most advanced technologies are largely worthless if they are never used to meet societal and economic needs.” 

Making Connecticut the “quantum capital of the world,” Alpay said, requires strong foundational relationships across five critical sectors: industry, academia, government, the broader community, and risk capital and entrepreneurship. He added that the engine has made significant progress since launching efforts to build Connecticut’s quantum economy in 2022.

“By building partnerships within our ecosystem, we have six new quantum startups in the state,” said Alpay. “The next step for quantum in Connecticut is the growth of a physical presence in New Haven, with convening spaces, test beds and an accelerator to support innovative ventures.” 

Piloting Drug Development Innovations

One academic partnership focused on developing quantum algorithms to help predict the safety of drugs under development.

QuantumCT awarded pilot grants to faculty at Yale University and the UConn to research how quantum-enabled technologies could reduce drug development costs and shorten production timelines. During the award period, companies including Pfizer brought real-world challenge sets to the QuantumCT team.

Faculty teams from both universities then worked with industry partners to identify potential quantum-based solutions. One university research team collaborated with Pfizer to develop quantum algorithms designed to predict drug safety earlier in the development process.

Alpay said the goal of QuantumCT projects is to firmly connect research to real-world applications and address current industry challenges.

“Quantum sounds futuristic, but it’s here right now, and by building partnerships between industry and academia, we can develop new products that help Connecticut’s major industries,” Alpay said. “The real outcomes of these partnerships are innovations that strengthen Connecticut businesses and grow our local economy.”

Expanding QuantumCT’s Footprint

The engine enabled UConn and Yale to collaborate at scale for the first time to address industry-defined challenges. Building on that success, QuantumCT has opened new communication channels among stakeholders to support expanded partnerships and investments, Alpay said.

“Sometimes it’s as simple as getting people into a room and having a conversation,” he said. “Other times, it involves investing research funding into industry challenge problems while ensuring engagement with workforce development and community education.”

Bolstering the Quantum Workforce

Alpay said effective quantum technologies will require a quantum-ready workforce. QuantumCT’s workforce development program aims to grow and sustain the quantum education ecosystem by creating experiential learning opportunities, such as industry apprenticeships, that provide relevant training for entry-level quantum workers.

QuantumCT’s workforce team has worked with industry partners for several years to identify future skill needs and has coordinated with state programs through Connecticut’s Office of Workforce Strategy.

“We are trying to build quantum literacy for those pursuing quantum-adjacent professions, such as business roles,” Alpay said. “We have an outstanding workforce development infrastructure, from kindergarten to retirement, that is ready and capable of training the quantum workforce of the future.”

Silvia Oakland | GovCIO | Original Article

Recent News

U.S. National Science Foundation Announces Transformational Award to Connecticut’s Quantum Tech Sector

For Immediate Release
July 14, 2026 —
WASHINGTON, D.C. — The U.S. National Science Foundation (NSF) announced today that
Connecticut is one of twelve regions selected to receive an NSF Regional Innovation
Engines (NSF Engines) award, joining a portfolio of regional technology clusters that are
accelerating the development of critical technologies and building a durable U.S.
technology advantage.
The NSF Quantum Technologies Engine in Connecticut, led by the University of
Connecticut in partnership with Yale University, Southern CT State University, Connecticut
State Community College, ConnCORP, CT Innovations, and the State of Connecticut, aims
to advance American quantum innovation and secure the domestic quantum supply chain
by accelerating the commercialization of quantum technologies for national defense,
biotechnology, and financial services. Through innovation, applied research leading to new
technologies, support for inventors and entrepreneurs, and workforce development, the
NSF Quantum Technologies Engine will advance quantum sensing, secured
communications, computing, and materials through shared testbed, deep-tech incubator
and translation pathways.
“NSF Engines investments in critical technologies and future industries will transform
America’s innovation infrastructure for decades to come,” says Brian Stone, performing the
duties of the NSF director. “The NSF Quantum Technologies Engine will advance the
Nation’s quantum innovation by accelerating the commercialization of quantum
technologies for national defense, biotechnology and financial services.”
The NSF Quantum Technologies Engine in Connecticut (the QuantumCT Engine) team will
initially receive a two-year, $15 million award. The funds will support the Engine’s
technology translation, workforce development, and incubator operations. The funds will
also facilitate industry and community engagement to deliver broad societal benefits. By
demonstrating sufficient progress, the QuantumCT Engine has the potential to receive
$160 million from NSF over the next decade.
The QuantumCT Engine will leverage world-leading research and innovation expertise from
UConn and Yale to pursue translational research to benefit industry, generate technology
ventures, and train the region’s workforce to enter a high-growth field. It will also deliver
technology acceleration and startup support services to drive public-private partnerships
and create a quantum ecosystem that generates economic growth.
Quantum technology industries are expected to grow to $200 billion by 2040, with the
potential to reshape sectors important to Connecticut and the country, including
aerospace, defense, drug development, manufacturing, and finance and insurance.
Connecticut companies that are adopting quantum technologies support over 270,000
jobs, accounting for 38% of wages in the state. They also are responsible for millions of
jobs and over $28.7 billion in GDP nationwide.
“Connecticut is the nation’s leading state for quantum technology adoption,” says Pamir
Alpay, UConn’s provost and the principal investigator on the NSF-funded proposal. “The
award recognizes our team’s success in establishing partnerships with industry to
accelerate quantum technologies and build a quantum-ready workforce.”
“This award application process was highly competitive, and it’s a huge win for
Connecticut,” says Gov. Ned Lamont. “Our pioneering research and advanced application
pipeline helped set us apart from the competition. Whereas other states may be theorizing
about quantum, we’re already applying it together with corporate partners across the state.
These federal funds, combined with state investment, will accelerate Connecticut’s
progress in quantum technology and help establish our state as a national and global
leader in this field—and we’re grateful for NSF’s support in getting us here. This investment
will help create good jobs and new opportunities for workers across the economy as
quantum’s impact grows.”
The NSF Engines program invests in regional ecosystems with the potential to drive
economic growth through technological innovation. The QuantumCT Engine proposal was
chosen for funding from a field of 15 finalists following a highly competitive national
selection process.
“As Connecticut’s flagship public university and the state’s land-grant institution, UConn
takes pride in its leadership role within the QuantumCT Engine. Our university is home to
more than 60 esteemed faculty members who are experts in the field of quantum science
and will collaborate with Yale researchers to drive innovative advancements and
groundbreaking discoveries in quantum research,” UConn President Radenka Maric says.
“Over the past three years, we have been working hand-in-hand with our academic, state,
industry, and community partners to position quantum technologies as a catalyst for
economic development that will fuel prosperity in our state and nation. It is crucial that
America take the lead in the global quantum race to safeguard national security, secure our
digital economy, and drive future economic growth. Furthermore, we must excel
internationally in quantum healthcare to deliver life-saving therapeutics and diagnostics. I
am grateful to Governor Lamont and Dan O’Keefe, the commissioner of the Department of
Economic and Community Development, for their grand vision for our state.”
The State of Connecticut has pledged $121 million to the QuantumCT Engine, comprising
$60 million already invested and an additional $60 million upon receiving the NSF award.
This state support will build a quantum incubator in New Haven, the Engine’s hub, among
other initiatives.
In 2023, NSF awarded the QuantumCT Engine team a $1 million NSF Engines Development
Award through UConn, which established the operational structure and built the
partnerships to drive the ecosystem. QuantumCT, a 501(c)(3) nonprofit organization, was
founded by UConn and Yale as part of the NSF Engine Development Award to support
applied research, help companies explore quantum applications, generate startups, and
prepare a skilled workforce.
Industry partners are key to the QuantumCT Engine’s success. Quantinuum and D-Wave
are partnering to develop quantum computing testbeds with QuantumCT that will be used
for experimentation and technology translation activities.
Quantum technology adopters – including RTX, Travelers, Boehringer Ingelheim, Pfizer,
Amphenol, and Microsoft – have been working with the QuantumCT Engine team over the
past several years on applied research projects that bring quantum capabilities directly to
their product lines.
“With this transformative award, NSF has recognized the scale of the QuantumCT Engine’s
ambition and its potential to accelerate the quantum revolution for our state, region, and
the United States as a whole,” Yale University President Maurie McInnis says.
“I am so proud of this effort to develop real-world solutions that enrich our communities
and of the spirit of collaboration that it represents,” she adds. “Together with our partners at
UConn and across the state, we have been able to drive innovation and unleash economic
growth, while fulfilling Yale’s vital mission of research and education.”
Alongside industry partnerships and state support, sustained investments by UConn and
Yale have helped build the quantum ecosystem that this award will accelerate.
At Yale, this includes startups such as Quantum Circuits, co-founded by Robert Schoelkopf
and Michel Devoret — whose pioneering work in quantum computing earned him the 2025
Nobel Prize in Physics — and recently acquired by tech innovator D-Wave with plans to
double its workforce in New Haven.
Southern Connecticut State University (SCSU) also plays a critical role as the QuantumCT
Engine’s workforce lead, with its QNT (CSCU Center for Quantum and Nanotechnology)
serving as the optimal coordinator based on its successes in leading educational initiatives
and strong alliances with industry, community stakeholders, and IHEs throughout
Connecticut.
Through longstanding technical and education collaborations with Yale, UConn, and the CT
State Community College System, the QNT is a conduit to all academic institutions in the
state and to small and medium businesses including those in advanced manufacturing,
biotech, photonics, and other supply chain sectors.
“Southern Connecticut State University is more than ready to take the lead on workforce
development in Connecticut’s quantum ecosystem,” says Sandra Bulmer, interim
president of the university. “We are proud to be part of Connecticut’s ‘research triangle,’
along with Yale and UConn, serving as the support for the talent pipeline. Our mission is
grounded in access and opportunity, and the workforce piece of this effort enables us to
open up new frontiers in research and innovation to countless students across
Connecticut.”

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